Hypertension is one of the most common worldwide diseases afflicting humans and is a major risk factor for stroke, myocardial infarction, vascular disease, and chronic kidney disease. Despite extensive research over the past several decades, the etiology of most cases of adult hypertension is still unknown, and control of blood pressure is suboptimal in the general population. Due to the associated morbidity and mortality and cost to society, preventing and treating hypertension is an important public health challenge. At present, it is estimated that about 1 billion people worldwide have hypertension (>140/90 mmHg), and this number is expected to increase to 1.56 billion by 2025. A similar scenario is seen in Pakistan. The National Health Survey of Pakistan estimated that hypertension affects 18% of adults and 33% of adults above 45 years old. In another report, it was shown that 18% of people in Pakistan suffer from hypertension with every third person over the age of 40 becoming increasingly vulnerable to a wide range of diseases. It was also mentioned that only 50% of the people with hypertension were diagnosed and that only half of those diagnosed were ever treated. Some remote areas like Baluchistan, there is a paucity of data but the control rate is likely to get even worse Hypertensive Nephrosclerosis is a disorder that is usually associated with chronic hypertension. In addition to the level of blood pressure, it is clear that individual factors are involved. As an example, black patients have an approximate eight-fold elevation in the risk of hypertension-induced end-stage renal disease; this increase in risk may persist even with "adequate" blood pressure control.